Any versions of the game is accessible, however i recommend you to get second encore since that one has an autodetect screen reader / sapi 5 right from the start without having to write a command to enable the clipboard. Not only that, in second encore all the text based story scenes is replaced with a fully voiced dialogs.
As for other accessible games on steam, you can by sequence storm, code 7 and alt frequencies.
going in to the wilds, collecting pokedex, and capturing them are my kind of thing,
training them, making them evolve, and generally making them stronger is my ultimate goal,
fighting other manamon tamers, winning the tournament, and fighting octoros are what these manamons like to do,
and ultimately, I become the master of mana!