Ill bet a decent margin. Maybe 3 percent or something. But remember big businesses and governments still pay top dollar to ensure their workforce
Good question though

They are undoubtedly aware, and you can't ever stop piracy, it's just a money pit you throw all your cash into to try to build defenses and protections that they take down in hours. I think the loss is negligible, for the reason that the enterprise customers like companies and schools are not going to get away with using cracks and the money they spend is going to outweigh the losses from the pirated versions.

To be honest, not that I'm taking sides, but I wouldn't be expecting anyone no matter there needs to pay 1000 GBP for software when, as post 1 rightly said, there are better alternatives out there.
In my opinion, if anything you would expect them to at least lower the price of acquiring a licence, as you could easily just download NVDA without having to pay possibly more than your computer just to have screen narration.

Ah cute, someone thinks FS makes most of their income with single purchase sales. As many people have pointed out, the main markets they make their profits from are government contracts and enterprise purchases. As well, there's the scripting scene to consider for interacting with comercial software/ creating scripts for custom private software for businesses. As well, this market is locked in, as some of the screen reader alternatives are open source, which is a no-no in sensitive-information managing institutions and businesses. Serving the single purchase is just a marketing tactic for showing they are an access company. but pricing (along with development concerns) mainly suggests the primary customer base can fling money of that constantly.

@ post 10. they've gotten worse through the years yes. many companies are okay to deal with. but FS is not good at all. When you speak to them out a individuals perspective you get given the boot. the moment you speak in the copacity of a business, guess what. that same individual now gets treated so sweetly.  It is sad, honestly it is. While they would love to rake in the few thousands they'd lose on revenue, they'd much rather keep the huge lions in check. to milk them. as for them  to try and chase the small little fish. Please do not get me wrong. Cracking there software is by no means the right thing to do. so answering the posters question is what i'd trie to do. In my opinion cracking the software is not even worth the time because the 40 minute demo already shows the horrible way it has degraded through the years. this topic is not about listing the reasons why this is so. so I only gave a general answer.  Please believe me when I say. I ay come over as hugely negative towards the software. This is not my intention. If anything, my intention is to point out the bad, so every one can be informed and for as long as the voices keep on talking. and not shutting up. and still telling them what is wrong. We are doing the right thing. would they listen? that remains to be seen. We can only hope.

I think freedem don't loos anything, because moestly, the crackers are from where that they can't buy the jaws

Oh no no no. They do care. they abselutely do. each update that JFW brings out has extra protection against the latest cracks. they are trying hard to circumvent the crackers, then the crackers crack the crack that could not be cracked that was fixed from cracking. And so on and so forth. Oh no, don't lose site of the fact that they are trying very hard to secure there software. and its the right thing of them to do. the only thing was they got in to a fix, due to there zeal of being to hard on authentic users of the software, they had to rework their authorisation strategy a bit

Yes I also find it ironic that they are spending all this money on trying to protect each new version when they could just be offering a better payment plan for individuals, even if it was only within English speaking countries at first.
I would estimate that they are probably losing between a quarter and half a million in sales from individuals at least, within the countries they sell to, but that's a very loose guess.
So it isn't nothing, but it's also probably less than the CEO's year end bonus.
As Manamon Player mentioned though, the rest of the people cracking surely wouldn't have been able to pay anyway even if they wanted to, so it's hard to call that an actual loss, although if you tallied it up, I imagine it would be several million dollars.
Now if they got their shit together and started figuring out a way to sell to those people, or at least the organizations in their countries that may be able to pay at a highly reduced price, than they could rake in a decent amount of extra cash up front even if update licenses would be few and far between.
I guess they just don't care enough?  Or maybe the component licensing costs they have to pay on each copy for things like OCR and voices are prohibitive?  But I don't see why they couldn't just sell a stripped down copy...
Honestly, I think they know that ship has sailed and that NVDA now takes up that potential market share they could have had if they would have bothered, so they are just letting it be when it comes to developing countries.
That's why they started up the annual plan, because they saw that they could still make money from developed countries and get a stable revenue stream out of it, but they are being slow in rolling it out to Canada, the UK, Australia, NZ ETC.

Annual plan for developing countries which is available only in US? Yep, that's the way you do it for sure.

As many others have said before me, I don't think FS cares that much about cracks. They're mostly focused on big enterprise/govt customers, mostly in the US. That's because american law requires companies to make workplaces accessible, which is not the case in most other countries. Big corps tend to trust other big corps like FS more than open source software. This is, in part, because Freedom Scientific, instead of providing just JAWS itself, provides some auxiliary services like technical  support, writing scripts that make custom, internal applications accessible etc. They even make Jfw work with some piece of software if a big corp needs it. They're focused on business applications like MS Office, and those work with JAWS really well, better than NVDA. They care a lot about efficiency, fast access to information etc. as all of this matters in the workplace. Individual customers are a nice bonus, not their main source of revenue. I wouldn't say that they made this decision out of sheer stupidity, they probably realized the the individual customers market is dominated by NVDA and smartphones, where JAWS doesn't run. They can get much more money out of providing JAWS at a very high price, selling it to companies, along with the additional services they need, of course.

One thing to note, though, is that the attitude to cracks isn't shared by other companies, particularly those who distribute FS products to other countries. For example, Altix, the FS dealer for Poland, modifies the polish version of JAWS and adds software to it. This software displays annoing alerts every few minutes unless you register your JAWS with Altix, and you can only do that if you purchased the serial with them. They try tp sell JFW to whomever they can, sometimes even to people who don't need it at all. There seems to be a coordinated efford by the dealers to spread FUD about NVDA. There have been some articles floating around, stating that NVDA is just two guys in a garage, that it might stop exist at any point, destroy your computer etc. Most of it is utter bs, of course.