This summer I have been working on a mod for Slay the Spire that provides screen reader accessibility. My goal is to provide a mod that is as close to the visual gaming experience as possible.
Public Beta 1 of the mod is now ready. Since the mod is in beta, not all of the planned features are fully implemented. Note that for now the mod only works with game controllers and keyboard support is not yet implemented.
The mod can be downloaded from GitHub https://github.com/bradjrenshaw/say-the-spire/ and installation instructions are also on that page.
The Steam Workshop page for the mod can be found here. If this link shows an error give it an hour or two and it should work.