So an update.
I restarted with 5 citizens. Far cry from reaching 10, but hey. Maybe next time.
I do wish that there could be some achievements added in, as well as the description of what you are buying. Some other mechanics, like corruption, crime, and technology could be blended in here as well.
I really, really want to continue building on this, as it's a good concept, just stale and shallow in some places.

And what does the billion dollar road even look like!

Though it's true that the costs are a bit stupid later on, perhaps the extra expensive road add more glory to your city? IDK.
Anyways. For me, the sweet time to run and reset seems to be in about 1 day.
I typically buy 100 roads, followed by 50 of everything else except the shopping and the bank center, those give me problems with their large numbers.
Anyways, got to 9 citizens this run, hoping that I will reach 25 this time (I had 5 when I started and added 9, or 180%, on this run).

WOW!
That is amazing, Nocturnus.
I am enjoying this game, even with the high numbers.

$54.197 Quintillion
Producing $438.868 Quadrillion per second
Next goal: 300 of all buildings
Current Citizens helping out
27,554
Upcoming helping Citizens
186,415 (677% of your current citizens)
Number of resets: 3
Time since last reset:About 11h 26m 44s
Date started: Mar 2, 2020

You need to get banks as well. I'm not sure if you know this, but there are global goals for getting certain numbers of all the buildings. So if you get at least 25 of everything, all profits double. Not to mention that banks look like a massive hurtle, and they are, but they will also make you the most money. You won't make big money if you never keep your banks up with the rest of your buildings.

Also, sorry for doubleposting, but don't forget the various kinds of upgrades you can buy; always check all the tabs and make sure you get whatever is going to make you the most profit.

So, to see the cost of buying a certain number of buildings, hover over the button with the number. ON NVDA you can do that with NVDA+Numpad slash on desktop layout, NVDA-shift-m on laptop layout, when focused on the button. IF you have mouse tracking enabled, NVDA should read the number when you do this, since your mouse is now on that button, and the next line will show the cost. If you mouse over the final button which lets you buy the max number of something all at once, it will tell you how many of that building you will actually buy, since the number on the button is rounded if it goes above 25 or so.

Quick question:
Upgrades bought with sacrificing citizens don't follow me to new city right?
I am thinking that maybe I wouldn't be bothering my self with them if they don't follow me to a new city since I have to wait a long time before I get 10000 citizens, the least I need to get a citizen upgrade.
However, if they do follow me to a new city that will make things a lot easier for me to get more upgrades and get more money.
I am currently at level 2 with 52 goals, have 8 goals left to reach level 3.

Yeah I know I'll be getting them again and even more.
However, my question is more about the upgrade it self if it follows me to a new city or not.
As it stands, I really can't sacrifice 10000 citizens right now, but I'll gladly do it if the citizen upgrades don't reset.
I don't know what is it about this game, but it's so addicting