You may try UbuntuMate. It is pretty accessible.

I'd try mate or vinux

Well having used ubuntu mate it works.
Vinux main website is no more it seems though there are downloads on the sourceforge site for it.
Same with sonar gnu linux which I did use once and is supposed to be a good arch distribution.
As you may or may not know, I have a cast called blindvms, www.cutt.us/blindvms for the rss
www.anchor.fm/blindvms or
www.mixcloud.com/crashmaster depending on what you want.
What is zorin os like, can it be used, or am I wasting my breath.
I may make an episode on zorin.
If you think its usefull, maybe you could even be in it, if you think its good tell me what is or isn't good about it and I will look at it.
II have to work later today so I may not get to it today but we will see.
I have a few more series on things to.

Vinux went EOL, i.e. no updates, no security patches, nothing at all since 04/19. Ubuntu Mate is easy to use and it is possible to install it with Orca from the live image.

It's the same deal with Accessible Coconut, but my issue with distros made specifically for blind users (which I've expressed before), is they come with a lot of software I don't personally think is useful at all. I don't need, for example in AC, two or three desktops, audio players and so forth. Ubuntu Mate is extremely good in this regard, it comes with what you need to get up and going.

On the Arch side, there's vanilla Arch, there's Jenux or the Free OS Project

Well to be honest as a precurser I tried a vm of zorin, just to see what it was like on the podcast before I made it.
Firstly the settings app just isn't usable in any shape or form, a screen of text but nothing else.
If you get a program with checkboxes you need to right arrow to the box then hit space on it.
The default gnome menus looked like menus, but no first letter nav, and no scrolling so up and down manually.
The software centre is accessible.
Its about the only gripe I have with ubuntu mate, software bootique just is a bunch of fucking unlabeled buttons.
Thats fine for what its worth but I wanted to doodle wiith it and see what it did.
There is no gnome sound in there, but I guess I could look for that later.
Orcer will not autoload at startup automatically after first start.
I may actually try it again just to see how really bad zorin is.
What I really want but can't seem to get with speech working right is siniman which mostly works.
I also want to know why ulsa audio is so wimpy in volume on my vms.

On the note of software things, one thing I'll say is get used to the terminal, it's a lot easier to open a terminal then type sudo apt install whatevder, or pacman -S whatever than fight with a software botique, personally, I'm used to the terminal simply because I find it a lot easier to use and quickerr and more detailed.

EDIT: Mate settings is a /lot/ more accessible however, it's all checkboxes and labled buttons however.

Except Ubuntu uses Gnome 3.X by default. See above for why it's not the most accessible.

I would like to ask I have installed vinella arch on many times on a vm but I could never really get sound working and now Debian I can no longer use because there is no speech on install. How is using slackware because I never really used it before and would like too.

My big issue with some of these things like debian in command mode was the fact that alsa speech was so fucking quiet as compaired to pulse audio that I had a hard time with it.
I don't know all the package names to install things, I have had it where an update to the software using apt get -upgrade suddenly completed but stopped me running commands and the vm stopped accepting them.
I forgot my password though so I killed the vm.
I'll put it back later when I have something to do with it.
Its a shame about zorinos though.
I didn't like the continuous menu scroling.
For me ubuntu mate just worked, but I am used to the old gnome2 system  on old fedora.
I'd still like a way to load everything one day.
Though my want to continue with linux has sort of stopped now I have managed to get dosbox to work with com0com and such.

Yeah I tried it on a vm, it was ok, but orca spoke comand keys and it was a bit slow.
Slint, well I never got it to install on the vm, speech would cut off either at login, during install or something.
Trying to login to a network needed a domain and password which I never had.
And I could never get fedora or others to even do the win alt s thing and never got things to work.

eI just installed Ubuntu Mate on my 2013 MacBook Air, and it actually works surprisingly well. I guess this distro isn't meant for really old computers with 2 GB of 667 MHz DDR RAM and an Intel Core Duo T2050 CPU? It's a shame, I thought this would work well on those older systems. The RAM usage is unbelieveable! System Info reports I'm only using 1.0 GB of RAM!

The only problems I have now are difficulties learning how Orca Flat Review works, and my Wi-Fi card isn't working. I have to use a USB Ethernet adapter. Any ideas?

I would just like to add that I am typing this post on a Debian Machine. I am using Mate as my desktop. This has been my daily machine for the last 9 years or so. I have had several versions of Debian on it, and the machine runs as fast at it did when I bought it.