Hi,
Whilst I can't speak to this years model, I do have the original qc35s and love them. Not only is the noise canceling simply superb, but the feel and quolity of them is simply excelent. As far as accessability is concerned, the IOS app that you can download is accessible for the most part and allows you to do things such as turn off/down noise canceling ETC.
HTH,

Daniel

Hi.
I have a few questions regarding the headset, since I might consider finding a replacement for my great old Bose headset:
1. Does the noise cancelation work when using the audio cable as well, and does the level of noise cancelation work which has been adjusted in the app when using the cable? I'm asking about this because I'm not sure if I can get used to the noise cancelation. I'm using my current Bose headset mostly with the audio cable instead of Bluetooth, but I find the Bluetooth option great to have.
2. Am I right that the newest model of the headset is using replaceable batteries? That's an interesting feature.
3. Is the Bose app totally accessible, and can you do other things than adjusting the noise cancelation level?

First of all, I have not trie the QC35 II with the audio cable. So, I do not really know how well the noise cancellation works on the audio cable. Yes, the bose app is mostly accessible. You, to some degree, have some trial and error when it comes to finding each setting, but once the location of each setting, you will find that they do not move. Yes, Bluetooth speakers and headphones have a delay. YOu do not really notice the delay when listening to music, but you will notice it when navigating around on your phone and the like. As for the batteries, the batteries are not replaceable. I am sorry about that. On the other hand, it takes the stander bacro USB cable for charging. I do use a different pair of headphones on my PC seeing that my PC does not have Bluetooth. I figure that sense that do not need noise cancellation and that I do need the audio cable to listen to music on my PC, I use the wired headphones that I linked to in my first posts seeing that I do like the sound just a tad better. This is not to say that the noise cancellation on the bose is bad, but I just like a slightly different sound when noise cancellation does not inter the picture.  I can also tell you that there is a big difference between cheep noise cancellation and good noise cancellation. I can also tell you that the noise cancellation stomps on the audio a bit, but that really can not be help seeing that it is what it is and it is not that bad either. Anyway, I tried these on the road and can say that they do block out most of the road noise. Yes, it can be a little off putting when you fill the road through the seat of the car while not receiving much of a hent through the sounds you are hearing that you are on the road. It is almost like the sound of a bedroom in your ears with the far distense of road noise while the the fill of the wheels on pavement of the road comes through the seat that you are sitting on. As a side note, I have no problem with the location of audio in the stario field when the audio source is through Bluetooth. Hope this helps.

I will have to check that out some time SLJ, but the madness of the Christmas and new year's holidays is putting that on hold for now as it were. On the other hand, I have read that the noise cancellation does work with the audio cable, but how well it does, I do not know seeing that I have not check it out yet. I also do not know for sure if it remembers the  level you set it to within the app, but it does seem to remember the other settings I have set. It is worth noting that I set the Butten on the left side to adjust the level of noise cancellation instead of the google thing to make a little more useful on my IOS devices seeing that the default setting only worked on IOS when the correct app was running. I can tell you that when you set the level via this Butten, it does not remember the level you have it set to when you turn the headset off. It made remember if you set it with the app itself, but I do not know. So, do I go with the name of headset here, or do I call them headphones instead? LOL. Anyway, now where did I put that cable Now...