Yes, it probably can. This is actually how game frameworks are generally designed, taking user input to trigger animations and sound effects within a given set of rules to create a "game". Developers however can, and do, often create scripted sequences, cutscene's, or animations within games that run without user input. In fact, you could create an entire film doing this with no user input at all, which is generally how pre-rendered animated 3D film's like those from Pixar are done. There's also [Machinima],  which makes use of game environments to record performances, although it can also involve scripted AI characters or events which can somewhat blur the lines between program scripted scenes and live performances.