Using Tolk is fairly easy, but to get it set up you need to collect a few files from the Tolk archive you downloaded and put them in your working directory with whatever script your working on.
After uncompressing it to, say, a directory called Tolk, go to "tolk/src/python/" and copy Tolk.py to your working directory.
Next go to "tolk/bin/x86/" and copy Tolk.dll to your working directory.
Then go to "Tolk/lib/x86/" and copy everything there to your working directory, which should be dolapi32.dll, nvdacontrollerclient32.dll, and saapi32.dll.
Now, tolk.py is the script you import to run Tolk, its a python wrapper for Tolk.dll. Tolk.dll uses the 3 other files, dolapi32, nvdacontrollerclient32, and saapi32, to interface with various types of screenreaders like NVDA. So, if you plan on distributing files you'll need to include all of these with your binary. Also, if your running on a 64 bit system, grab the files from the x64 folders instead of the x86 folders, so Tolk.dll from "tolk/bin/x64", and everything in "Tolk/lib/x64". Now to use Tolk with those files in your working directory just use commands like this:
#get tolks functions
#detect available screen readers
#check if braille, speech, or tolk are loaded
print(Tolk.has_braille(), Tolk.has_speech(), Tolk.is_loaded())
#if tolk is speaking, silence it
#have tolk speak
#output text to a braille display
#check if tolk is speaking
#when the program is finished, unload tolk
Keep in mind that Tolk will need some time to actually, you know, speak. So a better example might involve waiting and whatnot, but you get the idea.
: Accessible Paint Tool
: Accessible 3D Model Viewer