Well, I certainly can't say anything that even touches the advice of others here, as I agree with them all and they come from perspectives which I really don't have but which I think are more suited to helping you. But nevertheless I'll try to share mine.
I've chosen not to accept a religion as a major factor in my life, because I've always been a very logical thinker and a skeptic. I know that even deeply religious people can be logical thinkers and skeptics, but I found that trying to accept a religion couldn't explain things in a way that made a lot of sense to me. A religion brings more questions than answers in my mind.
As a small child, when my grandfather would tell me about God, I found what he was saying difficult to believe. Even the simple things such as God is watching you and knows if you're sinning or doing good things." Or, "All creatures are God's creatures. My first question is, "How does God watch billions of people?" "How did he make all those creatures?" My grandpa would gently try to preach to me, and as I saw it, he would beat around my questions.
"You're making this up aren't you?" I would ask.
"No no!" he insists, "This is all true.. "You should read the Bible," he continues in a friendly but serious tone. "I'm sure they make Braille bibles, just read a little every day and you will know a lot about God." He would recite random passages, no more than maybe a few lines, but it all sounded otherworldly to me.
"Who wrote this Bible?" I would ask. "And Pap, I don't want to say you're making this up but... how do you know these things are true? Because we do make-believe things all the time..."
That about did it.
"The Bible is the truth," he would say, with a hint of bewilderment in his voice. "But I can see you don't believe it so we won't talk about it."
My grandpa and I are very, very close. But that subject was one we never did see eye-to-eye on. He took my questions as resistance. He was afraid I'd go to school and start talking about how my grandpa tells these crazy God stories, or that I'd tell my parents and they'd get mad at him because they are not nearly so religious as he is. So he promptly stopped talking about it with me. To be honest that was probably a good idea, since I didn't always know what was and wasn't appropriate to discuss with different people.
As I got older, I gradually came to believe and accept that there may or may not be a God. If there is, he/it (I prefer to personify him) will one day show me there is one, and will understand why I've not been certain of him before. But how he will do that, I don't even think about. I'll give him the chance to do the things I do not understand, but I simply cannot accept him as definitive. I believe that all you have to do to get God's attention is to accept that he may exist. Someone once told me, "God is whatever you want it to be," and this is something I strongly identify with.
On the converse if there isn't a God at all, the world evolved simply through evolution, if there was nobody watching over us, etc. I'd honestly not be surprised. Like I say, this is more or less how I believed things were until I was told otherwise. I suppose actually reading a Bible and doing research would help me to understand a lot of the things I seem to be completely ignorant of here, but I actually like being ignorant of it in the most respectful way possible. If God is all-knowing, all-being, then as human beings who are not all-knowing and all-being, how can we try to speak for him. I believe we can't.
I don't pray or consciously ask for God's help for most of the reasons above. When I was little I thought prayer was a waste of time. You're just talking to the air. God isn't going to listen to our humble requests for his help, he'd rather you just have faith in him. For all I know, he might be like, "You again? Just go away. You're irritating me and you ask too much." Now I understand more or less why people do it, but I am not very sociable anyway, and talking to an empty room, or trying to talk about this with another person who likely won't be able to give my points a fair evaluation... they give me too much anxiety and discomfort, so I don't do it. Some people have told me that I will feel better about prayer if I remember God is listening to me and not judging. But then again, I can't be sure he exists. I can't bring myself to assume he is listening. To conclude this part of my rant, if I ever do find out one day if God is or is not real, I hope to accept it and not be disappointed. I'm somewhat prepared for either. And if I can, I will let you guys know what I find out.
But that's only part of what I came to this topic to say. Even though I wasn't religious, I still thought, for a long while, that being gay was wrong. Being trans was wrong. Being poly was wrong. Being bi was wrong... you get it. But, when going to college I actually met people who were all of those things. One of them was a trans, originally female, now male, going out with another male friend of mine. That really was a pivotal point of my life when I was talking to them both and said, you know what? It's okay. They feel how they feel. And as little as I'd want to parallel that path, I can almost understand why they follow it, as I deal with weird attractions and perspectives on my own. I'm a firm believer that you can only know what it entails if you've done it yourself, and because I have my own strange preferences and thoughts, I won't, at least not anymore, try to change or judge how others feel about similar issues. Sadly the relationship failed, but it had nothing to do with being trans or gay.
I haven't gotten to a point yet where I could accept a gay or trans person as a boyfriend or girlfriend... For the former I don't have gay feelings though I can be reeeally close to guys but it's not the same, and for the latter I would be uncomfortable for example if a girl was a guy originally. But if she was poly I would be okay with that because I *might* be so myself. I still don't know for sure.
So in conclusion, I have my own personal boundaries, and you do too, but don't blame your friend for changing her perspective during college and adult life. Perspective and religion go hand-in-hand. For many people, college is the first place to bring a wide variety of perspective in an environment more conducive to sharing that perspective. IN high school you simply don't get that because there is a firm structure in place. But in college there's more freedom. It's possible your friend has done what I did, and talked to a person or even a couple who has these issues under their belt which she says you are being closed minded about. Times do change, and I wouldn't want to live under a faith where God held my attractions and feelings against me, so long as I am living a good life that doesn't involve intentionally hurting others.
I won't lie, this is all probably easy for me to say since I accept nothing in a religious context as an absolute truth. But being agnostic as I am, I still wish to depart with some advice which I strongly encourage you to consider when speaking to your friend. Asking for God's acceptance is far easier than asking for the acceptance of people, and I believe that is precisely what your friend is seeing and is why she has called you closed-minded. Being closed-minded is something that most human beings are excellent at. It couldn't hurt you to open up and try to accept that her beliefs are warranted. You don't have to jump in head-first. It's a process to accept new controversial ideas. But fighting them just for the sake of sticking to the previous ways does make you closed-minded, as accusatory as it may sound.
Make more of less, that way you won't make less of more!
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