I played just a little bit, but I couldn't stream. Here are my thoughts so far.
Gameplay wise, it pretty much feels like Injustice1 from a casual standpoint. The returning characters have their same moves and combos. However, as they gain more items, they also gain additional moves. Now for competitive players, the game is faster than Injustice1 as we now have a meter burn dash that allows you to move across the screen extremely fast. it puts you in footsie range from your opponent resetting the neutral game. Most casuals like using the super moves, so this will probably not matter to them.
accessibility wise, the only thing now is the interactive sound cues. That's it. Characters don't seem to have sounds at the select screen like MKX or Injustice1. Also, it's difficult to figure out if you are playing in regular mode or tournament mode. All I know is that once players select their character, you are given the option to select custom or tournament mode. I'll do more research on this.
Ugh I wish my contact at NRS was still around.
There is more, but I haven't had the chance to fully explore. I'll try my best to keep this updated.