I use ESET NOD32. As far as I'm aware it hasn't failed me yet, though I'm not one who downloads a ton of crap from all over or opens email attachments from unknown sources. Accessibility isn't perfect but it's useable.

I use windows 32. Microsoft security esentials +Malwarebytes do it for me so far. There was only one time when mse didn't remove a virus I got, years ago, can't remember where I even got it. Everything else it found, though there were only one or 2 cases, anyway. The only thing I find annoying about mse is that whenever it believes a file is dangerous, it will delete it, often without warning. This is very helpful usually, but there are some very much false warnings. Not a big deal though, you can allways just disable it for 2 minutes.
Never heard of clamwin, will look it up.

On both computers with windows 10 (home edition - 64 bit), I have left it all down to windows defender. I do not pay too much attention to security. I am safe as long as I don't visit potentially harmful websites or instal apps from sources I don't trust. I also have used Panda, free antivirus, plus another of this line to scan the USB. I have this panda antivirus on my old laptop where I installed windows 7

@turtlepower17,
unfortunately, your sources are correct, at least to some degree.  Clamwin is the kind of software I'd recommend to people who, a, don't do a lot of heavy browsing, b, know what they're doing within most of the operating system and, C, love open source.  It's not the set and forget I remember MSE being.  It fails in a ton of areas and has no realtime monitoring.
Keep them coming, people!

Hello.

I use Vipre. I can't remember what vertion it is, There's two, one is for internet browsing and the other is a virus scanner. I think it might be the internet browsing version as I can scan and sites are blocked at times.

Accessibility: I'd say this program is about 98 percent accesssible. You can do everything from scanning to setting up the firewall, however, you will need to know how to navigate using NVDA'S flat review or object review, I'm not sure what other screen readers call this. It's basicly an invisible curser mode that allows you to click on things that the normal keyboard shortcuts won't allow you to click on.

I'd recommend Googleing vipre and trying the demo. I think you'll like it.

Isn't it true that Avira has constant popup ads that encourage you to upgrade to the paid version? When I was weighing my options and thinking of which antivirus to switch to after breaking up with Vipre, Avira was one I'd considered due to its decent accessibility and good ratings. But then I heard about the ads, and I said, no thank you.

at Nocturnus, that's true. I don't mind so much about there being no real-time protection, thus why I used it as a backup to catch stuff that Eset didn't. Actually, it was more for peace of mind than anything, given that I haven't encountered any real threats in quite awhile now. Anyway, I heard that the malware detection engine itself is flawed, which is why I ditched Clamwin. I wasn't happy about doing it, though. The interface was clutter free and extremely accessible. I was also perfectly content to set up scheduled scans, although I can see how the average user might not know about this feature.

Coming back to my antivirus, Panda free antivirus, I'd recommend a product of this line called USB vaccine. This so-called small program scans your USB and removes a small but very nerve-racking virus which turns the content of your USB into a shortcut, therefore forcing you to click on it to show your files and folders. I always install this program and once clicking vaccinate computer button, your computer is safe from this virus. The interface of this program is accessible via touch cursor mode with JAWS, and via object navigation (NVDA).
Hope this helps you.

My only issue with msse is that it finds programs its not had any issue with as a virus.
So right now thats pipe 1 by blindsoftware and yesterday gma dice by gmagames.
In both cases it needs to restart, I do, then I have to reinstall that game, exclude it, then turn off uac which has been set to 34%.
I use malwarebytes if I think I have a big issue but I have noscript, better privacy and a few things like that in firefox.
The only time I could get a virus bar spam messages is if I actually unknowing clicked a file addware excluded.
A few installers like ccleaner have become a bit inaccessible but unchecky has been good for me for a while.
A lot have been saying sophos is good, so have vipre, trouble is I really like the fact its accessible and just works I don't need to check what its doing and yeah resources are still an issue.
Maybe after I get a 64 bit unit later with 8gb ram it won't matter that much.
I do like the idea of cloud protection.
Am I assuming with sophos that if I exclude something its stored online so it will remain excluded for ever more?
Also what is their pro products like.
I do eventually want to buy if not for the remote users a home security suite which is itself accessible.

Ahoy there
This is a really good topic and something I have wanted peoples views/reviews on, now and then, quite often.

While to keep ones pc secure all one needs is a bit of common sense and a okayish antivirus, sometimes its better to have a good one on just in case common sense doesn't work all the time or the antivirus you have just isn't enough.

When it comes to acessibility and antiviruses or protection the choices are indeed quite limited. and a topic like this should help all of us to know or have a central resource for getting the information on what's accessible and what works and what doesn't

On my old pc I used to have bitdefender installed, the standard version since a good scanner/ antivirus engine is all I needed and internet security is just too much for my needs plus ataking up more resources as compared to the standard one.
I got primarily because of its good reviews when it came to ditection and clean up.
However, its the most inaccessible software I have ever come across, so I'd need sighted help to configure it and stuff.
It does have a autopilot mode which when enabled doesn't require hardly any atention at all, but yes,unfortunatly its not a software a visually impaired/ screenreader user can use on their own.
One good thing about it as compared to others is its fairly lite on system resources even with its good virus engine.

On my mbp running windows8.1 primarily I'm using nothing but windows defender along with a addblocker on firefox
grryf

Slightly off topic, but somewhat relevant too. I was reminded of this by Crashmaster's comments about false positives.

A couple of days ago I decided to take a look at GMA's Lone Wolf submarine simulation. I normally have Microsoft's Smart Screen filtering turned on, but had to temporarily turn it off because it kept blocking the download of Lone Wolf because it thought it was unsafe.

Curiously it was also the only GMA download that I got notices about it not being signed or that the publisher couldn't be determined. When I contacted GMA about both problems with their file, the response I got, gave me the impression that they didn't care. So I installed it in a sand box for now.

I use kaspersky. It's not very accessible, but I can do what I need to with object nav. It's apparently pretty good. I actually only use it because it's what the rest of my family uses, and my dad buys one with multiple licenses so I might just as well. I also use firefox with noscript and self-destructing cookies.
I don't agree you're fine without an antivirus though. I also don't think I've ever gotten malware from the internet, but I've often gotten from other people's flash discs. And although this hasn't happened to me yet several people I know have gotten viruses from university pcs or printers. So even though you're safe on the internet it's sometimes impossible to avoid getting malware from people who aren't.